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Biomolecular structure and function

1. Biomolecular structure and function · Part-A: General Biotechnology

BIOMOL.STRUCTURE Biochemistry

Covers the covalent architecture of proteins, nucleic acids, carbohydrates and lipids, plus the weak forces that fold them.

10 sub-topics

Open any one for its reading list, most-cited papers and cross-exam appearances.

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01

Covalent structure of amino acids, proteins, nucleic acids, carbohydrates and lipids

BIOMOL.STRUCTURE

02

stabilizing forces (electrostatic and van der Waals interactions, hydrogen bonding, interactions with solvents, hydrophobic effect)

BIOMOL.STRUCTURE

03

protein structure (alpha-helix, beta-sheet, beta-turn characteristics, Ramachandran plot, protein domains and domain architecture, quaternary structure)

BIOMOL.STRUCTURE

04

conformation of nucleic acids (A, B and Z-DNA

BIOMOL.STRUCTURE

05

3D structure of t-RNA, ribozymes, riboswitches)

MOLBIO.TRANSCRIPTION

06

basic thermodynamics (laws, delta G, delta H, delta S)

BIOENERGETICS

07

physical properties of water and their role in biology

BIOMOL.STRUCTURE

08

pH, ionic strength, buffers

BIOPHYS.CHEM

09

chemical kinetics (order and molecularity, first- and second-order rate equations, measurement of rate constants, activation energy)

BIOMOL.STRUCTURE

10

enzymology (types of enzymatic reaction mechanisms, Michaelis-Menten kinetics, competitive, non-competitive and un-competitive inhibition, bisubstrate reaction kinetics, allostery)

BIOPHYS.CHEM