SyllabusScope

Fundamentals of Biological Engineering

BT4: Fundamentals of Biological Engineering · GATE BT

ENZYME_TECH Biotechnology

Biocatalysis in non-natural conditions, enzyme engineering and immobilised enzyme or whole-cell reactors.

2 sub-topics

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01

Bioreaction engineering (rate laws, Michaelis-Menten and inhibition kinetics, ideal reactors, enzyme immobilization, Thiele modulus, effectiveness factor, Damkohler number, cell growth, substrate and product kinetics, structured and unstructured models, batch, fed-batch and continuous, microbial and enzyme reactors, optimization and scale-up)

  • ENZYME_TECH
02

upstream and downstream processing (media formulation and optimization, sterilization of air and media, filtration and ultrafiltration, centrifugation, cell disruption, chromatography principles, extraction, adsorption and drying, measurement devices, valves, first- and second-order systems, feedback and feed-forward control, controller types and tuning)

  • DOWNSTREAM